Radiesse is an injectable product for lip enhancement and the filling of folds and lines. The advantage of this product is the potential for a long-lasting effect. Radiesse consists of calcium hydroxylapatite suspended in gel (carboxymethylcellose). Because calcium hydroxylapatite is a normal constituent of bone, it should not elicit a chronic inflammatory or immune response. Additionally, the gel carrier doesn’t require allergy testing such as required with collagen. 


Studies and use of the injectable product in vocal chords and bladder neck areas have shown that the product remains soft without new bone formation when injected into soft tissue. 

Calcium hydroxylapatite has been used for a long time in prosthetic implants in dental, facial and orthopedic surgery. 

The longest-term studies come from Italy and suggest that Radiance shows promise as a new agent for facial contouring with no serious side effects and reasonable efficacy and durability.